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Insilico Develops The World’s First Fully AI-Generated Drug
The Abu Dhabi-based company hopes to treat idiopathic pulmonary fibrosis, and has 30 more drugs in the pipeline.
In a busy biotech hub in Abu Dhabi’s Masdar City, Insilico Medicine is pushing the frontiers of science. Under the watchful eye of Latvian-born CEO Dr Alex Zhavoronkov, the company has developed an AI-generated drug to treat idiopathic pulmonary fibrosis (IPF) — a deadly disease of the lungs.
“This AI drug is a major milestone for us and the industry as a whole,” Dr. Zhavoronkov explains. “We can use AI to create lifesaving treatments for new diseases using approaches we haven’t yet considered and do so much more rapidly and efficiently”.
Idiopathic pulmonary fibrosis is characterized by scarring of the lungs and has no known cure. Insilico’s AI drug aims to halt or even reverse the progression of IPF and is currently undergoing Phase 2 clinical trials in the US and China. The success of these trials will pave the way for more in-depth testing, bringing the drug closer to mass market approval.
Insilico’s groundbreaking research was recently published in Nature Biotechnology. It highlights how the company’s AI platform, Pharma.AI, is connecting the dots between fibrosis and aging to drive forward the discovery of a cure.
IPF treatment is just the beginning for Insilico. The company already has a roadmap consisting of over thirty AI-designed drugs, with seven already in clinical patient trials. These include treatments for inflammatory bowel disease, immuno-oncology targets, and even drugs developed using a method that targets a protein in cancers that can kill them without harming healthy cells.
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Dr Zhavoronkov’s ultimate goal is to leverage AI to unravel the complex processes involved in aging. “Our number one priority is to teach AI to understand the basic biology of aging, and I think we’ve succeeded in that process. Now, we need to demonstrate that we can utilize this understanding to cure diseases,” he says.
Insilico Medicine’s AI-driven drugs showcase the massive untapped potential of artificial intelligence in all aspects of healthcare. As the company continues to innovate, its work brings hope to patients around the world and demonstrates that the future of medicine is promising, thanks to the application of the latest technological breakthroughs.
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Abu Dhabi’s Robot Kitchen Is Serving Up Biryani, Not Burgers
Circus SE wants to put a tiny automated factory inside the buildings where Gulf residents live and work, bypassing part of last-mile delivery.
The most telling thing about a new autonomous kitchen now running in Abu Dhabi’s Marina Square is what it won’t cook:
“We don’t do fast food,” says Nikolas Bullwinkel, Founder and CEO of Circus SE. “We’ve actively decided not to build a machine that can only do burgers”.
Instead, the CA-1 system is built around pot-based cooking: curries, pastas, soups and rice dishes. After experimenting with highly personalized recipes, Circus deliberately leaned back toward recognizable food. “We’re going with a chicken biryani because you know it,” Bullwinkel says of the AED 40 dish.
The Germany-based robotics and food technology company operates across eight countries, and Abu Dhabi is its first deployment outside Europe. More locations are expected there and in Dubai.
In Germany, its units can be placed in supermarkets, gas stations, airports and hospitals. In the Gulf, Bullwinkel wants them inside residential and office buildings, replacing some of the complexity of last-mile delivery. “We’re basically bringing a very tiny factory a few square meters into your building,” he says. Catering company Royal Prestige supplies the ingredients and knowledge of local tastes.
The CA-1 manages up to 36 refrigerated ingredient silos alongside automated induction cooking, robotic plating and a self-cleaning dishwasher. Two robotic arms move ingredients through the system with minimal human intervention. It can produce up to 120 hot meals an hour, and a meal such as rice and curry can take around three to four minutes.
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Five cameras and multiple sensors monitor heat, temperature and consistency, an attempt to approximate what a chef perceives. “You can hear something gets burned, you can smell it, you can see it at some point,” Bullwinkel says. CircusOS, the company’s operating system, adjusts recipes in real time.
You might think of the platform as a threat to kitchen staff, but Bullwinkel frames Circus as a way for chefs to develop recipes and distribute them at scale. With that being said, rising labor costs and shortages are also part of his case for automation.
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