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Insilico Develops The World’s First Fully AI-Generated Drug
The Abu Dhabi-based company hopes to treat idiopathic pulmonary fibrosis, and has 30 more drugs in the pipeline.
In a busy biotech hub in Abu Dhabi’s Masdar City, Insilico Medicine is pushing the frontiers of science. Under the watchful eye of Latvian-born CEO Dr Alex Zhavoronkov, the company has developed an AI-generated drug to treat idiopathic pulmonary fibrosis (IPF) — a deadly disease of the lungs.
“This AI drug is a major milestone for us and the industry as a whole,” Dr. Zhavoronkov explains. “We can use AI to create lifesaving treatments for new diseases using approaches we haven’t yet considered and do so much more rapidly and efficiently”.
Idiopathic pulmonary fibrosis is characterized by scarring of the lungs and has no known cure. Insilico’s AI drug aims to halt or even reverse the progression of IPF and is currently undergoing Phase 2 clinical trials in the US and China. The success of these trials will pave the way for more in-depth testing, bringing the drug closer to mass market approval.
Insilico’s groundbreaking research was recently published in Nature Biotechnology. It highlights how the company’s AI platform, Pharma.AI, is connecting the dots between fibrosis and aging to drive forward the discovery of a cure.
IPF treatment is just the beginning for Insilico. The company already has a roadmap consisting of over thirty AI-designed drugs, with seven already in clinical patient trials. These include treatments for inflammatory bowel disease, immuno-oncology targets, and even drugs developed using a method that targets a protein in cancers that can kill them without harming healthy cells.
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Dr Zhavoronkov’s ultimate goal is to leverage AI to unravel the complex processes involved in aging. “Our number one priority is to teach AI to understand the basic biology of aging, and I think we’ve succeeded in that process. Now, we need to demonstrate that we can utilize this understanding to cure diseases,” he says.
Insilico Medicine’s AI-driven drugs showcase the massive untapped potential of artificial intelligence in all aspects of healthcare. As the company continues to innovate, its work brings hope to patients around the world and demonstrates that the future of medicine is promising, thanks to the application of the latest technological breakthroughs.
News
Truecaller For iPhone Gets Real-Time Caller ID And Auto Spam Blocking
The latest update integrates with Apple’s Live Caller ID Lookup framework, launched with iOS 18 last year.
Truecaller has rolled out a major update for iPhone users, introducing API support that brings real-time caller identification and automatic spam blocking. The upgrade aims to bring the iOS version of the app closer to its Android counterpart, which has long offered these advanced call-screening features.
The latest update integrates with Apple’s Live Caller ID Lookup framework, launched with iOS 18 last year. The technology allows third-party apps to cross-check incoming calls against a database of known spam numbers in real-time. Importantly, the process employs “homomorphic encryption,” ensuring user privacy by masking the caller’s number, concealing the client’s IP address, and using anonymous authentication.
With this update, Truecaller has also introduced global automatic spam call blocking for iPhones. However, the real-time caller ID feature is being released gradually and is available only to Truecaller Premium subscribers on iPhones running iOS 18.2 or later. Free users will still have access to ad-supported features, such as manual number searches and caller identification for verified businesses.
How To Enable The New Features
To activate the new features, follow these steps:
- Update the Truecaller app to version 14.0 or newer via the App Store.
- Go to Settings > Apps > Phone > Call Blocking & Identification on your iPhone.
- Turn on all Truecaller toggles, then restart the app.
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While these features are new to iOS, Truecaller has hinted at this update for months. Following Apple’s iOS 18 update and the introduction of its Live Caller ID API last September, Truecaller Co-founder Alan Mamedi shared his excitement on X (formerly Twitter), saying, “Truecaller finally works on iPhone”.
The global rollout of spam call blocking is already live, but users may need to wait for gradual access to the live caller ID feature.
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