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NYU Abu Dhabi Develops Cancer-Fighting Nanospheres

The biotech breakthrough promises safer and more effective treatments using photodynamic and photothermal therapies.

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1 year ago

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nyu abu dhabi develops cancer-fighting nanospheres
NYU Abu Dhabi

A Research team from NYU Abu Dhabi’s Magzoub lab has made considerable advances in the fight against cancer using biocompatible nanospheres that have the potential to replace traditional forms of treatment.

The experiments trialed photodynamic therapy (PDT) and photothermal therapy (PTT), which use non-invasive light waves to destroy cancers, avoiding the well-known side effects of chemo and radiotherapy.

Photodynamic therapy works by releasing a torrent of reactive oxygen species (ROS) onto cancer cells, whereas photothermal therapy converts light into searing heat, destroying tumor tissues through hyperthermia.

The research team has detailed their findings in a paper entitled “pH-Responsive Upconversion Mesoporous Silica Nanospheres for Combined Multimodal Diagnostic Imaging and Targeted Photodynamic and Photothermal Cancer Therapy”. The literature goes on to explain how the nanospheres are able to protect encapsulated photosensitizers and photothermal agents from degrading, enabling them to be delivered directly to cancer cells.

Alongside thermal and fluorescent imaging, traditional magnetic resonance imaging (MRI) is also used for tumor detection and monitoring. Once cancer is detected, the PDT and PTT can kill tumors without leaving toxic traces in the body.

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Loganathan Palanikumar, a senior researcher in the NYUAD Magzoub lab, explained the process, “To make PDT effective, we need enough photosensitizer in the tumor tissue, while PTT requires a substantial accumulation of photothermal agents within tumors”.

Mazin Magzoub, NYUAD associate professor of biology and Magzoub lab leader, added, “New therapeutic approaches are desperately needed to enhance the existing arsenal of cancer-fighting treatments”.

Magzoub lab’s new treatments offer real hope that cancers could soon be treated with minimal stress and danger to patients, leading to a brighter future free from one of the world’s most feared and destructive diseases.

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UAE Prepares To Launch Two Satellites: Thuraya-2 And MBZ-SAT

HH Sheikh Hamdan bin Mohammed bin Rashid Al Maktoum chaired the first meeting of the Supreme Space Council yesterday.

Published

5 days ago

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December 17, 2024

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uae prepares to launch two satellites thuraya-2 and mbz-sat

HH Sheikh Hamdan bin Mohammed bin Rashid Al Maktoum, Crown Prince of Dubai and Deputy Prime Minister of the UAE, chaired the first meeting of the Supreme Space Council in Dubai on December 16, 2024. The session highlighted the UAE’s ambitious space plans and took stock of the sector’s economic progress.

The council emphasized the growing role of private companies in advancing space technologies, noting that their contributions are now equal to that of the public sector. Members also praised initiatives like the Space Economic Zones Programme, which are designed to fuel innovation and investment in the space industry.

Discussing the UAE’s space journey, HH Sheikh Hamdan bin Mohammed bin Rashid Al Maktoum remarked, “The national space sector continues to grow and advance, and we take immense pride in the remarkable achievements we have accomplished over the years”.

Sheikh Hamdan also received updates on two upcoming satellite projects: Thuraya-2 and MBZ-SAT. Thuraya-2, developed by Space42, is slated for launch this December. Meanwhile, the MBZ-SAT, created by the Mohammed Bin Rashid Space Centre (MBRSC), will soon follow. MBRSC, a major driver of the UAE National Space Programme, continues to lead the nation’s space-related developments.

Space42 took the opportunity to showcase its advancements, including ongoing collaborations between public and private entities. The company also outlined strategies to promote innovation, boost revenue streams, and create new opportunities for growth in the sector.

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The UAE’s current projects build on a growing legacy of space exploration. Back in 2020, the nation made headlines with its Mars mission, successfully sending a probe into the planet’s orbit in 2021. This mission, which is now in its second phase as of June 2024, has been collecting critical data to develop a comprehensive diurnal image of Mars.

The UAE also ventured into lunar exploration with an unmanned mission aimed at studying untouched regions of the Moon’s surface. While the probe ultimately crashed during its landing attempt after communication was lost seconds before touchdown, the effort represented a significant step in the country’s exploration ambitions.

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