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NYU Abu Dhabi Develops Cancer-Fighting Nanospheres
The biotech breakthrough promises safer and more effective treatments using photodynamic and photothermal therapies.
A Research team from NYU Abu Dhabi’s Magzoub lab has made considerable advances in the fight against cancer using biocompatible nanospheres that have the potential to replace traditional forms of treatment.
The experiments trialed photodynamic therapy (PDT) and photothermal therapy (PTT), which use non-invasive light waves to destroy cancers, avoiding the well-known side effects of chemo and radiotherapy.
Photodynamic therapy works by releasing a torrent of reactive oxygen species (ROS) onto cancer cells, whereas photothermal therapy converts light into searing heat, destroying tumor tissues through hyperthermia.
The research team has detailed their findings in a paper entitled “pH-Responsive Upconversion Mesoporous Silica Nanospheres for Combined Multimodal Diagnostic Imaging and Targeted Photodynamic and Photothermal Cancer Therapy”. The literature goes on to explain how the nanospheres are able to protect encapsulated photosensitizers and photothermal agents from degrading, enabling them to be delivered directly to cancer cells.
Alongside thermal and fluorescent imaging, traditional magnetic resonance imaging (MRI) is also used for tumor detection and monitoring. Once cancer is detected, the PDT and PTT can kill tumors without leaving toxic traces in the body.
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Loganathan Palanikumar, a senior researcher in the NYUAD Magzoub lab, explained the process, “To make PDT effective, we need enough photosensitizer in the tumor tissue, while PTT requires a substantial accumulation of photothermal agents within tumors”.
Mazin Magzoub, NYUAD associate professor of biology and Magzoub lab leader, added, “New therapeutic approaches are desperately needed to enhance the existing arsenal of cancer-fighting treatments”.
Magzoub lab’s new treatments offer real hope that cancers could soon be treated with minimal stress and danger to patients, leading to a brighter future free from one of the world’s most feared and destructive diseases.
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AltoVolo Opens Orders For Limited Edition Sigma eVTOLs
Early buyers can now reserve build slots for AltoVolo’s 500-mile hybrid aircraft through a new online configurator.
AltoVolo has started taking pre-orders for its first electric vertical take-off and landing aircraft, the Sigma, moving the startup closer to commercial rollout. Customers can now secure a build slot with a £860 deposit and customize every detail online — from paintwork to seatbelt stitching. It’s the first configurator of its kind for a civilian eVTOL, mirroring how luxury car brands let clients tailor performance models before production.
The Sigma runs on a hybrid-electric tilting jet system built for long range and low noise. It can travel up to 500 miles at a 220-mph cruise, and is over 80% quieter than a helicopter. The three-seater weighs just 980kg and can maintain stable flight even if one jet fails. Safety systems include triple-redundant controls, thrust-vectoring stability and a ballistic parachute.
“We will be delivering an ultra-refined hybrid electric aircraft,” said founder and CEO Will Wood. “We believe there are thousands of customers for this type of cutting-edge technology”.
The first 100 units will come with exclusive materials and finishes. AltoVolo is also setting up a global service and maintenance network, with early planning for overhaul schedules already underway. The company’s focus on ownership experience echoes its ambition to anchor itself alongside established aviation brands rather than pure tech ventures.
To help new owners train, the company has built a full-scale simulator that replicates the Sigma cockpit in carbon fiber and leather. Pilots can log time toward a license using the system, aligned with the new US MOSAIC rules that ease certification for powered-lift aircraft. Certification work in Europe and the UK continues in parallel, signaling growing international alignment around light sport and eVTOL regulation.
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Noise inside the cabin has become another design focus. Engineers are refining internal vibration levels and developing a responsive soundscape that shifts with each jet’s power load — part feedback, part theatre.
Urban air mobility projects across the Gulf and elsewhere are pushing regulators and manufacturers to meet in the middle. Dubai, Riyadh and Doha have each outlined plans for air taxi corridors this decade. AltoVolo’s hybrid Sigma, sitting between electric promise and aviation realism, looks built for that middle ground.
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