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Abu Dhabi Scientists Create Electronic Appetite Regulation Pill

The tiny device utilizes electrodes to stabilize and regulate the gut-brain axis, which can help control appetite and treat several diseases.

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abu dhabi scientists create electronic appetite regulation pill
NYUAD

A research team from NYU Abu Dhabi (NYUAD), overseen by Professor Khalil Ramadi, has created a groundbreaking “ingestible electroceutical device” known as the FLASH system. The pill-shaped device modulates the signaling pathway between the digestive tract and the central nervous system and is administered like a regular ingestible capsule tablet.

Featuring surface electrodes that deliver stimulation to the stomach’s mucosal tissues, the non-invasive device bypasses gastric acids to achieve direct electrode-to-tissue contact. The ingestible pill is powered by tiny batteries, delivering stimulation for around 20 minutes before being excreted by the body — a process that can take up to two weeks, depending on the size of the human or animal test subject.

the flash system appetite regulation pill

“FLASH is one of the first ingestible electroceuticals that can regulate precise neurohormonal circuits while avoiding the discomfort patients can experience with invasive treatments,” says Professor Khalil Ramadi, NYU Abu Dhabi.

Researchers on the FLASH project were inspired by the unique skin surface properties of the Australian Thorny Devil Lizard, whose skin can efficiently wick away surface moisture. The pill replicates this process by using grooved surface patterns and hydrophilic properties that enable it to be ingested and excreted without side effects.

Also Read: Sultan Al Neyadi Becomes The First Ever Arab To Spacewalk

During testing, scientists noted that the capsule modulated the release of the hormone ghrelin, which the body uses to stimulate hunger. Regular hormone medications have poor bioavailability in oral form, requiring an injection to administer. The FLASH system, on the other hand, can target very specific gastric-hormonal pathways through simple oral administration.

The FLASH pill shows promise against a wide range of diseases, including metabolic, gastrointestinal, and neuropsychiatric disorders. Unfortunately, the device requires further preclinical testing before being ready for the public market. However, the development team has set a goal of creating an advanced prototype for human trials within five years.

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Abu Dhabi’s Robot Kitchen Is Serving Up Biryani, Not Burgers

Circus SE wants to put a tiny automated factory inside the buildings where Gulf residents live and work, bypassing part of last-mile delivery.

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abu dhabi's robot kitchen is serving up biryani not burgers
Circus SE

The most telling thing about a new autonomous kitchen now running in Abu Dhabi’s Marina Square is what it won’t cook:

“We don’t do fast food,” says Nikolas Bullwinkel, Founder and CEO of Circus SE. “We’ve actively decided not to build a machine that can only do burgers”.

Instead, the CA-1 system is built around pot-based cooking: curries, pastas, soups and rice dishes. After experimenting with highly personalized recipes, Circus deliberately leaned back toward recognizable food. “We’re going with a chicken biryani because you know it,” Bullwinkel says of the AED 40 dish.

circus se ca-1 robot system

The Germany-based robotics and food technology company operates across eight countries, and Abu Dhabi is its first deployment outside Europe. More locations are expected there and in Dubai.

In Germany, its units can be placed in supermarkets, gas stations, airports and hospitals. In the Gulf, Bullwinkel wants them inside residential and office buildings, replacing some of the complexity of last-mile delivery. “We’re basically bringing a very tiny factory a few square meters into your building,” he says. Catering company Royal Prestige supplies the ingredients and knowledge of local tastes.

The CA-1 manages up to 36 refrigerated ingredient silos alongside automated induction cooking, robotic plating and a self-cleaning dishwasher. Two robotic arms move ingredients through the system with minimal human intervention. It can produce up to 120 hot meals an hour, and a meal such as rice and curry can take around three to four minutes.

Also Read: Ooredoo Qatar’s 5G+ Network Is Built For Machines As Much As People

Five cameras and multiple sensors monitor heat, temperature and consistency, an attempt to approximate what a chef perceives. “You can hear something gets burned, you can smell it, you can see it at some point,” Bullwinkel says. CircusOS, the company’s operating system, adjusts recipes in real time.

You might think of the platform as a threat to kitchen staff, but Bullwinkel frames Circus as a way for chefs to develop recipes and distribute them at scale. With that being said, rising labor costs and shortages are also part of his case for automation.

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