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Abu Dhabi Scientists Create Electronic Appetite Regulation Pill

The tiny device utilizes electrodes to stabilize and regulate the gut-brain axis, which can help control appetite and treat several diseases.

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abu dhabi scientists create electronic appetite regulation pill
NYUAD

A research team from NYU Abu Dhabi (NYUAD), overseen by Professor Khalil Ramadi, has created a groundbreaking “ingestible electroceutical device” known as the FLASH system. The pill-shaped device modulates the signaling pathway between the digestive tract and the central nervous system and is administered like a regular ingestible capsule tablet.

Featuring surface electrodes that deliver stimulation to the stomach’s mucosal tissues, the non-invasive device bypasses gastric acids to achieve direct electrode-to-tissue contact. The ingestible pill is powered by tiny batteries, delivering stimulation for around 20 minutes before being excreted by the body — a process that can take up to two weeks, depending on the size of the human or animal test subject.

the flash system appetite regulation pill

“FLASH is one of the first ingestible electroceuticals that can regulate precise neurohormonal circuits while avoiding the discomfort patients can experience with invasive treatments,” says Professor Khalil Ramadi, NYU Abu Dhabi.

Researchers on the FLASH project were inspired by the unique skin surface properties of the Australian Thorny Devil Lizard, whose skin can efficiently wick away surface moisture. The pill replicates this process by using grooved surface patterns and hydrophilic properties that enable it to be ingested and excreted without side effects.

Also Read: Sultan Al Neyadi Becomes The First Ever Arab To Spacewalk

During testing, scientists noted that the capsule modulated the release of the hormone ghrelin, which the body uses to stimulate hunger. Regular hormone medications have poor bioavailability in oral form, requiring an injection to administer. The FLASH system, on the other hand, can target very specific gastric-hormonal pathways through simple oral administration.

The FLASH pill shows promise against a wide range of diseases, including metabolic, gastrointestinal, and neuropsychiatric disorders. Unfortunately, the device requires further preclinical testing before being ready for the public market. However, the development team has set a goal of creating an advanced prototype for human trials within five years.

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Adobe Teases New AI Editing Tools And Updates In Premiere Pro

The video editing app will be enhanced with a generative extend tool, text-to-video, improved timeline waveforms, and more.

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adobe teases new ai editing tools and updates in premiere pro
Adobe

After launching the generative AI model Firefly last year, Adobe is now showcasing how the technology will be used in upcoming versions of the editing app Premiere Pro. In an early sneak peek, the company demonstrated several new features, including Object Addition and Removal, Generative Extend, and Text to Video.

The first new feature, Generative Extend, targets a common video editing problem by using AI to “Seamlessly add frames to make clips longer, so it’s easier to perfectly time edits and add smooth transitions”.

Meanwhile, Premiere Pro’s Object Addition & Removal tool will leverage Firefly’s generative AI to “Simply select and track objects, then replace them. Remove unwanted items, change an actor’s wardrobe or quickly add set dressings such as a painting or photorealistic flowers on a desk,” Adobe states.

Adobe also showcased another new feature that can automatically generate new film clips using a text prompt. To use the content creation tool, editors can “Simply type text into a prompt or upload reference images. These clips can be used to ideate and create storyboards, or to create B-roll for augmenting live action footage,” Adobe explained. The company seems to be commercializing this particular feature extremely quickly, considering generative AI video only appeared a few months ago.

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The new additions to Premiere Pro will be added later this year, but Adobe is also introducing smaller improvements to the editing app in May. The changes include interactive fade handles to enable easier transitions, an Essential Sound badge that uses AI to “automatically tag audio clips as dialogue, music, sound effects or ambience, and add a new icon so editors get one-click, instant access to the right controls for the job”, along with effect badges and a new look for waveforms in the timeline.

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