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Abu Dhabi Scientists Create Electronic Appetite Regulation Pill

The tiny device utilizes electrodes to stabilize and regulate the gut-brain axis, which can help control appetite and treat several diseases.

Published

3 years ago

May 3, 2023

Nour Nasir

abu dhabi scientists create electronic appetite regulation pill

NYUAD

A research team from NYU Abu Dhabi (NYUAD), overseen by Professor Khalil Ramadi, has created a groundbreaking “ingestible electroceutical device” known as the FLASH system. The pill-shaped device modulates the signaling pathway between the digestive tract and the central nervous system and is administered like a regular ingestible capsule tablet.

Featuring surface electrodes that deliver stimulation to the stomach’s mucosal tissues, the non-invasive device bypasses gastric acids to achieve direct electrode-to-tissue contact. The ingestible pill is powered by tiny batteries, delivering stimulation for around 20 minutes before being excreted by the body — a process that can take up to two weeks, depending on the size of the human or animal test subject.

the flash system appetite regulation pill

“FLASH is one of the first ingestible electroceuticals that can regulate precise neurohormonal circuits while avoiding the discomfort patients can experience with invasive treatments,” says Professor Khalil Ramadi, NYU Abu Dhabi.

Researchers on the FLASH project were inspired by the unique skin surface properties of the Australian Thorny Devil Lizard, whose skin can efficiently wick away surface moisture. The pill replicates this process by using grooved surface patterns and hydrophilic properties that enable it to be ingested and excreted without side effects.

Also Read: Sultan Al Neyadi Becomes The First Ever Arab To Spacewalk

During testing, scientists noted that the capsule modulated the release of the hormone ghrelin, which the body uses to stimulate hunger. Regular hormone medications have poor bioavailability in oral form, requiring an injection to administer. The FLASH system, on the other hand, can target very specific gastric-hormonal pathways through simple oral administration.

The FLASH pill shows promise against a wide range of diseases, including metabolic, gastrointestinal, and neuropsychiatric disorders. Unfortunately, the device requires further preclinical testing before being ready for the public market. However, the development team has set a goal of creating an advanced prototype for human trials within five years.

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Microsoft Plans $10 Billion-Plus Gulf Expansion Despite Iran Conflict

Security is shaping Microsoft’s approach, from resilience work with governments to what it will say about how the money splits by country.

Published

4 days ago

September 24, 2026

Nour Nasir

Microsoft

Microsoft is planning more than $10 billion of investment across the UAE, Saudi Arabia, Qatar and Kuwait through 2030, Vice Chair and President Brad Smith told Reuters, calling the spending schedule aggressive. The Iranian conflict that began on February 28 has not persuaded the company to scale back.

“We’re sustaining all the investments we planned to make before this conflict started, and we are in fact adding to them,” Smith said. The $10 billion-plus total does not, however, show how large those additions are.

The investment, which Smith described as part of Microsoft’s continued infrastructure expansion, is aimed at cloud and AI infrastructure and at the company’s growing regional operations. Microsoft also intends to put more than $400 million into subsea and terrestrial connectivity across the Middle East by 2030.

The spending fits the region’s own ambitions too. Gulf governments have been investing heavily in AI infrastructure as part of a push to diversify their economies beyond oil and gas and turn themselves into global technology hubs. Major cloud and AI providers have been drawn in part by the land and relatively low-cost energy on offer.

Microsoft is widening its partnerships with regional AI companies, though not on identical terms. In 2024, it invested $1.5 billion in Abu Dhabi-based G42 for a minority stake, and Smith currently sits on G42’s board. Saudi Arabia’s Humain and Qatar’s Qai are working with Microsoft on selected priority areas, but Smith said the company does not plan to make capital investments in either.

Also Read: Egypt’s Mobile Wallets Are Booming, But Cash Still Has Power

The conflict has added another strand to Microsoft’s work in the region. Since it began, Smith said, the company has supported regional partners with digital resilience assessments, and it is now working with Gulf countries through a digital resilience initiative focused on preparedness and the protection of critical data.

So far, the company has given no country-by-country breakdown of the investment, citing security among other factors. So while the headline figure is public, how Microsoft divides the spending among the four countries is not.